| Thursday, October 2nd |
Session 1: Cell Death Molecular Mechanisms and Pathways
Chair: Marie-Lise GOUGEON [Institut Pasteur, Paris, France] |
| 09:00 |
- |
09:30 |
Gerry MELINO [MRC Toxicology Unit, Leicester, UK]
TAp73 Regulates Tumour Angiogenesis by Promoting Hypoxia-inducible Factor-1α Degradation |
| 09:30 |
- |
10:00 |
Jiri BARTEK [Danish Cancer Society, Kopenhagen, Denmark]
Cellular Responses to Genotoxic Stress: Mechanisms and Relevance for Tumorigenesis and Cancer Treatment |
| 10:00 |
- |
10:30 |
Boris TURK [Stefan Institute, Ljubljana, Slovenia]
Lysosomes: at the Crossroad between Cell Death and Survival |
| 10:30 |
- |
11:00 |
Coffee Break |
| 11:00 |
- |
11:30 |
Kodi RAVICHANDRAN [University of Virginia, Charlottesville, USA]
Benefits of Apoptotic Cell Recognition and Cell Clearance |
| 11:30 |
- |
11:45 |
Short Talk 1:
Liming SUN [Institute of Biochemistry and Cell Biology, Shanghai, China]
Necrosome Core Machinery: MLKL |
| 11:45 |
- |
12:00 |
Short Talk 2:
Guy BROWN [University of Cambridge, UK]
Caspace-8 Inhibition Induces Necroptosis Specifically in Activated Microglia, Preventing their Phagoptosis of Neurons |
| 12:00 |
- |
12:30 |
Peter VANDENABEELE [VIB Inflammation Research Center, Gent, Belgium]
Molecular Mechanisms of Necroptosis: Old Paradigms Come Back |
| 12:30 |
- |
13:00 |
Carlos IBANEZ [Karolinska Institute, Stockholm, Sweden]
Genetic Dissection of Death Receptor Signalling |
| 13:15 |
- |
14:30 |
Lunch Break |
Session 2: Inflammation
Chair: Peter VANDENABEELE [VIB Inflammation Research Center, Gent, Belgium] |
| 14:30 |
- |
15:00 |
Seamus MARTIN [Trinity College, Dublin, Ireland]
Cell Death and Inflammation |
| 15:00 |
- |
15:30 |
George KOLLIAS [BSRC "Alexander Fleming", Athens, Greece]
TNFR Signalling in the Mesenchyme and Physiological Roles in Chronic Inflammatory Disease |
| 15:30 |
- |
15:45 |
Short Talk 3:
Geert VAN LOO [Ghent University, Belgium]
A20 in Inflammatory Signaling and Pathology |
| 15:45 |
- |
16:15 |
Manolis PASPARAKIS [CECAD Research Center, Cologne, Germany]
RIP Kinases in Cell Death and Inflammation |
| 16:15 |
- |
16:45 |
Junyin YUAN [Harvard Medical School, Boston, USA]
Regulation of the RIP1 Kinase at the Crossroad of Cell Death and Inflammation |
| 17:00 |
- |
18:30 |
POSTER SESSION 1 |
| 17:00 |
- |
18:00 |
ECDO Board Meeting |
| 20:00 |
|
|
Gala Dinner |
| Friday, October 3rd |
Session 3: Degradation Processes and Cell Death
Chair: Mauro PIACENTINI [University of Rome, Italy] |
| 09:00 |
- |
09:30 |
Ding XUE [University of Colorado, Boulder, USA]
Targets of Caspases -- Death by A Few Cuts |
| 09:30 |
- |
10:00 |
David WALLACH [Weizmann Institute of Science, Rehovot, Israel]
Anti-inflammatory Functions of Caspase-8 |
| 10:00 |
- |
10:30 |
Ivan DIKIC [Goethe University School of Medicine, Frankfurt, Germany]
Linear Ubiquitination in Cell Death Pathways |
| 10:30 |
- |
11:00 |
Coffee Break |
| 11:00 |
- |
11:30 |
Kevin RYAN [Beatson Institute for Cancer Research, Glasgow, UK]
Autophagy in Cell Death and Cancer |
| 11:30 |
- |
11:45 |
Short Talk 4:
Luizi LEANZA [University of Padua, Italy]
Targeting and Ion Channel for Selective Elimination of Cancer Cells in vivo |
| 11:45 |
- |
12:00 |
Short Talk 5:
Joseph OPFERMAN [St. Jude Children’s Research Hospital, Memphis, USA]
Identifying Strategies to Inhibit Anti-Apoptotic MCL-1 in Philadelphia Chromosome Acute Lymphoblastic Leukemia |
| 12:00 |
- |
12:30 |
Bertrand JOSEPH [Cancer Centrum Karolinska, Stockholm, Sweden]
The Return of the Nucleus: Epigenetic Control of Autophagy |
| 12:30 |
- |
14:00 |
Lunch Break |
Session 4: Autophagy
Chair: Alexander PINTZAS [National Hellenic Research Foundation, Athens, Greece] |
| 14:00 |
- |
14:30 |
Guido KROEMER [INSERM, Paris, France]
Therapeutic Modulation of Autophagy |
| 14:30 |
- |
15:00 |
David RUBINSZTEIN [Cambridge Institute for Medical Research, Cambridge, UK]
Autophagy - from Neurodegeneration to the Plasma Membrane |
| 15:00 |
- |
15:30 |
Patrice CODOGNO [INSERM, Paris, France]
STK38 Kinase is a New Beclin 1 Partner required for Autophagosome Formation |
| 15:30 |
- |
15:45 |
Short Talk 6:
Andreas VILLUNGER [Medical University Innsbruck, Austria]
Combined Loss of the BH3-only Protein Bim and Bmf Restores B Cell Development and Function in TACI-Ig Mice |
| 15:45 |
- |
16:00 |
Short Talk 7:
Sylvie LEFEBVRE [Inflammation Research Center, VIB, Ghent, Belgium]
The Kinase RIPK1 Acts as a Guardian of Skin Homeostasis |
| 16:00 |
- |
16:30 |
Patricia BOYA [Spanish National Research Council, Madrid, Spain]
Autophagy, Cell Death and Aging |
| 16:30 |
- |
18:30 |
POSTER SESSION 2 |
ECDO Keynote Lecture & General Assembly
Chair: Guido KROEMER [University Paris Descartes, Paris, France] |
| 18:30 |
- |
19:15 |
ECDO Keynote Lecture
Xin LU [The Ludwig Institute for Cancer Research, Oxford, UK]
From Cell Death to Sudden Death: Cardiotoxicity Revisited |
| 19:15 |
- |
19:30 |
Poster Awards |
| 19:30 |
- |
20:00 |
ECDO General Assembly |
| Saturday, October 4th |
Session 5: Ageing and Regeneration
Chair: Boris ZHIVOTOVSKY [Karolinska Institute, Stockholm, Sweden] |
| 09:00 |
- |
09:30 |
Frank MADEO [University of Graz, Austria]
From Dying Yeasts to Longevity Drugs |
| 09:30 |
- |
10:00 |
Daren BAKER [Mayo Clinic, Rochester, USA]
Targeted Apoptosis to Improve Animal Healthspan |
| 10:00 |
- |
10:30 |
Brigitte GALLIOT [University of Geneva, Switzerland]
Cell Death, a Program to Regenerate in Hydra |
| 10:30 |
- |
11:00 |
Coffee Break |
| 11:00 |
- |
11:30 |
Luca SCORRANO [University of Padova, Italy]
Keeping Mitochondria in Shape: A Matter of Life and Death |
| 11:30 |
- |
12:00 |
Thomas LANGER [University of Cologne, Germany]
Mitochondrial Quality Control and Neurodegeneration |
| 12:00 |
- |
12:15 |
Short Talk 8:
Anne HAMACHER-BRADY [German Cancer Research Center, Heidelberg, Germany]
Canonical BH3-only Proteins Trigger Macroautophagy-independent, Ubiquitin-mediated Intramitochondrial Processing |
| 12:15 |
- |
12:45 |
Nektarios TAVERNARAKIS [IMBB-FORTH, University of Crete, Heraklion, Greece]
Coordination of Mitophagy and Mitochondrial Biogenesis during Ageing |
| 12:45 |
- |
13:00 |
Closing Remarks |
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